Which patient groups have higher incidence of familial Mediterranean fever (FMF)?

Updated: May 14, 2018
  • Author: John O Meyerhoff, MD; Chief Editor: Herbert S Diamond, MD  more...
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Answer

In adults, FMF is more prevalent in men than in women, with a male-to-female ratio of 1.5-2:1.

Of all persons with FMF, 50-60% are younger than 10 years, 80-95% are younger than 20 years, and 5-10% are older than 20 years at onset. Onset in persons older than 40 years is rare. In a retrospective review, 5 of 18 heterozygous children with onset below age 6 years went into remission at puberty and were able to stop colchicine. [13]


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