Which medications in the drug class Combination drugs are used in the treatment of Gout and Pseudogout?

Updated: Jan 26, 2021
  • Author: Bruce M Rothschild, MD; Chief Editor: Herbert S Diamond, MD  more...
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Answer

Combination drugs

Uricase facilitates conversion of urate to allantoin. Unlike uric acid, allantoin is soluble and easily excreted by the kidneys. Thus, hyperuricemia is reduced, with little risk of acute kidney injury.

Gout is a highly symptomatic and painful form of inflammatory arthritis caused by hyperuricemia, or elevated serum uric levels in the blood, which can lead to painful flares and serious potential long-term health consequences. Combination treatments provide a new option in the treatment of both gout and hyperuricemia.

Lesinurad/allopurinol (Duzallo)

Fixed-dosed combination indicated for treatment of hyperuricemia associated with gout in patients for whom target serum uric acid (sUA) levels have not been achieved with allopurinol alone.


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