What is the role of anakinra (Kineret) in the treatment of acute attacks of gout?

Updated: Jan 26, 2021
  • Author: Bruce M Rothschild, MD; Chief Editor: Herbert S Diamond, MD  more...
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Answer

Desmarais and Chu reported that anakinra (Kineret), an interleukin-1 receptor antagonist that is primarily indicated for rheumatoid arthritis, is an effective and safe treatment for acute gout and pseudogout in hospitalized patients, particularly those with comorbidities that limit treatment choices. In their study of hospitalized patients with acute gout (n = 77), pseudogout (n = 11), or both (n = 3), 92% of gout flares and 79% of pseudogout flares responded to treatment. Patients tolerated anakinra well. [148]


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