Does urate-lowering therapy increase the risk of gout flares?

Updated: Jan 26, 2021
  • Author: Bruce M Rothschild, MD; Chief Editor: Herbert S Diamond, MD  more...
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In a study of gout flares in patients newly started on urate-lowering therapy, Rashid et al found that 68% of these patients had one or more gout flares during the first 12 months of therapy. [133] Patients 65 years of age and older were more likely to have three or more flares.

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