What are complications of gout?

Updated: Jan 26, 2021
  • Author: Bruce M Rothschild, MD; Chief Editor: Herbert S Diamond, MD  more...
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Complications of gout include the following:

  • Severe degenerative arthritis
  • Secondary infections
  • Urate or uric acid nephropathy
  • Increased susceptibility to infection
  • Urate nephropathy
  • Renal stones
  • Nerve or spinal cord impingement [95, 96]
  • Fractures in joints with tophaceous gout [97]

Calcification of the atlas transverse ligament has been reported in 44-70% of individuals with calcium pyrophosphate disease (CPPD), with frequency increasing with age. [98] A significantly elevated rate of non-union of type II and III odontoid fractures has been reported in patients with CPPD (90.3%, versus 32% in controls). [99]

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