Which antidepressants have been approved for use in fibromyalgia?

Updated: Nov 14, 2018
  • Author: Chad S Boomershine, MD, PhD, CPI, CPT; Chief Editor: Herbert S Diamond, MD  more...
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Answer

Milnacipran has been approved for use in fibromyalgia by the FDA. Duloxetine has been shown to improve pain in fibromyalgia irrespective of comorbid depression [139] and is currently approved by the FDA for pain in fibromyalgia. SNRIs can cause nausea, so they should be taken with food.


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