When is antinuclear antibody (ANA) or rheumatoid factor (RF) testing indicated in the workup of fibromyalgia?

Updated: Nov 14, 2018
  • Author: Chad S Boomershine, MD, PhD, CPI, CPT; Chief Editor: Herbert S Diamond, MD  more...
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Answer

Routine antinuclear antibody (ANA) or rheumatoid factor (RF) testing in not recommended unless patients have signs or symptoms concerning for systemic lupus erythematosus (SLE) or rheumatoid arthritis. A low-titer positive ANA or RF level is common in the general population, so these findings may be of no clinical significance in a fibromyalgia patient.


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