Which medications in the drug class Immunosuppressive agents are used in the treatment of Behcet Disease?

Updated: Dec 21, 2020
  • Author: Nicole Davey-Ranasinghe, MD; Chief Editor: Herbert S Diamond, MD  more...
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Answer

Immunosuppressive agents

These agents decrease the immune response that causes signs and symptoms of Behçet disease.

Azathioprine (Imuran)

Purine analog that inhibits DNA synthesis. The 50-mg tablets are metabolized to 6-mercaptopurine in the liver and RBCs.

Cyclophosphamide (Cytoxan, Neosar)

Potent alkylating agent that inhibits various cellular functions. Alkylation of DNA results in cross-linking, impaired DNA synthesis, and cell death.

Chlorambucil (Leukeran)

Potent alkylating agent that inhibits various cellular functions. Alkylation of DNA results in cross-linking, impaired DNA synthesis, and cell death. Onset of action is slower than cyclophosphamide.


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