What is the role of antiphospholipid antibody testing in the workup of Behçet disease?

Updated: Dec 21, 2020
  • Author: Nicole Davey-Ranasinghe, MD; Chief Editor: Herbert S Diamond, MD  more...
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Answer

These include lupus anticoagulant, dilute Russell viper venom test (DRVVT), and anticardiolipin antibodies. Although such antibodies are uncommon in Behçet disease, they are worth investigating to rule out alternate causes of thrombosis.

Up to one third of patients with Behçet disease who have thrombosis are found to have factor V Leiden–deficiency mutations. Therefore, antiphospholipid antibodies and other causes of hypercoagulability should be ruled out as contributing factors to thrombosis formation.


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