Which vascular findings are characteristic of Behçet disease?

Updated: Dec 21, 2020
  • Author: Nicole Davey-Ranasinghe, MD; Chief Editor: Herbert S Diamond, MD  more...
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Answer

Lower-extremity superficial thrombophlebitis often presents in a linear fashion with overlying erythema and tenderness. Palpation of sclerosed thrombophlebitis yields subcutaneous stringlike quality.

Deep venous thrombosis (DVT) develops in some cases and typically manifests as local tenderness or as disparity in limb girth.

Saadoun et al found that cerebral venous thrombosis (CVT) was present in 7.8% of a large cohort of patients with Behçet disease. The main complication of CVT was severe visual loss due to optic atrophy. Papilledema and concurrent prothrombotic risk factors were independently associated with the occurrence of sequelae; peripheral venous thrombosis and concurrent prothrombotic risk factors were associated with relapse of thrombosis. Anticoagulant therapy proved safe and effective in up to 90% of patients. [41]

Arterial vasculitis may manifest as claudication symptoms.


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