What are the cardiac and pulmonary manifestations of Behçet disease?

Updated: Dec 21, 2020
  • Author: Nicole Davey-Ranasinghe, MD; Chief Editor: Herbert S Diamond, MD  more...
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Answer

Cardiac manifestations (5-17% of cases) include the following::

  • Coronary vasculitis and thrombosis
  • Pericarditis
  • Endocarditis with granulomatous changes or fibrosis
  • Regurgitation
  • Diastolic dysfunction

Lung involvement occurs in up to 18% of patients with Behçet disease. Pulmonary vasculitis, hypertension, and pleural effusions have been reported. Aneurysms represent a dreaded complication of Behçet disease and may result in massive hemoptysis. The detection of a pulmonary aneurysm in the setting of a vasculitic illness is highly suggestive of Behçet disease. [39]

 


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