What indicators predict the severity of hand pain in women with carpal tunnel syndrome (CTS), and what is the relation of distal radius fracture to CTS?

Updated: Mar 30, 2020
  • Author: Nigel L Ashworth, MBChB, MSc, FRCPC; Chief Editor: Milton J Klein, DO, MBA  more...
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A study by Fernández-Munoz et al reported that in women with CTS, the following predict the severity of hand pain [29] :

  • Function

  • Thumb-middle finger pinch tip grip force

  • Thumb-little finger pinch tip grip force

  • Depression

  • Pressure pain threshold (radial nerve)

  • Pressure pain threshold (carpal tunnel)

  • Heat pain threshold (carpal tunnel)

The study, which involved 224 women with CTS, indicated that these factors are responsible for 36.5% of variance in pain intensity.

A study by Yeh et al indicated that in patients who suffer a distal radius fracture, CTS is more likely to develop, within a 9-month postfracture period, in those who undergo open reduction and internal fixation (ORIF). The investigators also reported that the presence of diabetes mellitus was significantly associated with the development of CTS within 9 months following distal radius fracture (adjusted hazard ratio 2.76). [30]

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