What is the composition of methylprednisolone used in corticosteroid injections for joints and soft tissue injuries?

Updated: Jan 15, 2020
  • Author: Jess D Salinas, Jr, MD; Chief Editor: Elizabeth A Moberg-Wolff, MD  more...
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The material used for the injection is left to the discretion of the physician. Numerous philosophies and theories exist regarding the use of the different materials that are available. [29] Many physicians prefer a simple, long-acting methylprednisolone preparation. This author prefers a cocktail consisting of equal parts of the following:

  • Lidocaine

  • Triamcinolone, which is intermediate acting (40 mg/mL)

  • Dexamethasone, which is long acting (4 mg/mL)

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