What is the role of alpha-adrenergic blockers and anticholinergics in the treatment of middle cerebral artery (MCA) stroke?

Updated: Feb 20, 2018
  • Author: Daniel I Slater, MD; Chief Editor: Stephen Kishner, MD, MHA  more...
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Answer

Answer

Treatment of uninhibited bladder resultant from stroke may include the use of alpha-adrenergic blockers or anticholinergics. Of the alpha-adrenergic blockers, tamsulosin is associated with less orthostatic hypotension than terazosin, doxazosin, prazosin, and alfuzosin. [89] Anticholinergics such as oxybutynin and tolterodine may also be used. The newer longer-acting antimuscarinic agents have fewer adverse effects and may promote better adherence. [90]


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