Which biochemical screens should be performed in the workup of suspected Guillain-Barre syndrome (GBS)?

Updated: May 04, 2018
  • Author: Michael T Andary, MD, MS; Chief Editor: Milton J Klein, DO, MBA  more...
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Answer

Biochemical screening includes the following studies:

  • Electrolyte levels

  • Liver function tests (LFTs)

  • Creatine phosphokinase (CPK) level

  • ESR

The following should be considered:

  • LFT results are elevated in as many as one third of patients

  • CPK and ESR may be elevated with myopathies or systemic inflammatory conditions

  • A stool culture for C jejuni and a pregnancy test are also indicated

  • The syndrome of inappropriate antidiuretic hormone (SIADH) may occur


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