What is the global incidence of Guillain-Barre syndrome (GBS)?

Updated: May 04, 2018
  • Author: Michael T Andary, MD, MS; Chief Editor: Milton J Klein, DO, MBA  more...
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Answer

GBS has been reported throughout the world. [68, 69] Most studies show annual incidence figures similar to those in the United States, without geographical clustering. AMAN and AMSAN occur mainly in northern China, Japan, and Mexico, making up only 5-10% percent of GBS cases in the United States. [70] AIDP accounts for up to 90% of cases in Europe, North America, and the developed world.

Epidemiologic studies from Japan indicate that in this region, in comparison with North America and Europe, a greater percentage of GBS cases are associated with antecedent C jejuni infections and a lesser number are related to antecedent CMV infections. Similarly, it has been reported that 69% of GBS cases in Dhaka, Bangladesh, have clinical evidence of antecedent C jejuni infection. [31]


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