What is the general etiology of Guillain-Barre syndrome (GBS)?

Updated: May 04, 2018
  • Author: Michael T Andary, MD, MS; Chief Editor: Milton J Klein, DO, MBA  more...
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Answer

GBS is considered to be a postinfectious, immune-mediated disease targeting peripheral nerves. Up to two thirds of patients report an antecedent bacterial or viral illness prior to the onset of neurologic symptoms. [22, 23] Respiratory infections are most frequently reported, followed by gastrointestinal infections. [24] Administration of certain vaccinations and other systemic illnesses have also been associated with GBS. Case reports exist regarding numerous medications and procedures; however, whether any causal link exists is unclear.


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