Which histologic findings are characteristics of Scheuermann disease (juvenile kyphosis)?

Updated: Sep 08, 2020
  • Author: Jozef E Nowak, MD; Chief Editor: Stephen Kishner, MD, MHA  more...
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  • Histologic changes demonstrate that vertebral growth endplate cartilage is abnormal, with a decreased collagen/proteoglycan ratio on electron microscopic examination.

  • Enchondral ossification is altered profoundly in affected segments, and there are increased proteoglycan levels.

  • The matrix of the endplates is abnormal, thus interfering with normal vertebral growth.

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