Which medications in the drug class Analgesics are used in the treatment of Chronic Pain Syndrome?

Updated: Jan 14, 2020
  • Author: Manish K Singh, MD; Chief Editor: Stephen Kishner, MD, MHA  more...
  • Print


Analgesics are commonly used for many pain syndromes. Pain control is essential to quality patient care. Analgesics ensure patient comfort, promote pulmonary toilet, and have sedating properties, which are beneficial for patients who have sustained traumatic injuries.

Oxycodone (OxyContin, Roxicodone)

Long-acting opioids may be used in patients with CPS. Start with a small dose and, if appropriate, gradually increase it.

Fentanyl (Duragesic, Fentora, Onsolis, Actiq)

Fentanyl is a potent narcotic analgesic with a much shorter half-life than morphine sulfate. It is the drug of choice for conscious-sedation analgesia. Fentanyl is ideal for analgesic action of short duration during anesthesia and during the immediate postoperative period. It is an excellent choice for pain management and sedation of short duration (30-60min).

Fentanyl is easy to titrate and is easily and quickly reversed by naloxone. When the transdermal dosage form is used, most patients achieve pain control with 72-hour dosing intervals; however, some patients require dosing intervals of 48 hours.

Acetaminophen (Tylenol, FeverAll, Aspirin Free Anacin)

Acetaminophen is the drug of choice for the treatment of pain in patients with documented hypersensitivity to aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs), with upper GI disease, who are pregnant, or who are taking oral anticoagulants.

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!