What is the risk of fibromyalgia associated with chronic pain syndrome (CPS)?

Updated: Jan 14, 2020
  • Author: Manish K Singh, MD; Chief Editor: Stephen Kishner, MD, MHA  more...
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Answer

Results from a study by Mork et al indicated that women who are overweight or obese have a 60-70% greater risk of developing fibromyalgia than do women of normal weight, with body mass index (BMI) being an independent risk factor for the condition. The report looked at whether physical exercise and high BMI influence the occurrence of fibromyalgia. The study included 15,990 women, none of whom at baseline had fibromyalgia or any other physical impairment. By 11-year follow-up, incident fibromyalgia had reportedly occurred in 380 women. The authors noted that only a weak association typically existed between exercise level and fibromyalgia risk.

In overweight or obese women in the study who exercised for at least 1 hour each week, the relative risk (RR) for fibromyalgia (in comparison with women of normal weight and a similar activity level) was 1.72, while in overweight or obese women who did not exercise or who did so for less than an hour per week, the RR was 2.09. [10]


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