What is the role of spondylolisthesis in the pathophysiology of mechanical low back pain?

Updated: Mar 06, 2018
  • Author: Everett C Hills, MD, MS; Chief Editor: Stephen Kishner, MD, MHA  more...
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Answer

A review study by Raastad et al of radiographic features in patients with LBP found that in community- and occupation-based studies, such pain was significantly associated with disk-space narrowing. LBP was also significantly linked with the presence of spondylolisthesis, but in occupation-based studies only. The review, which involved 28 studies (26,107 subjects total), also indicated that LBP has only a weak association with spondylosis and osteophytes and a nonsignificant association with endplate sclerosis. [14]


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