What is the prognosis of patellofemoral syndrome (PFS)?

Updated: Sep 15, 2020
  • Author: Noel F So, MD, FAAPMR; Chief Editor: Consuelo T Lorenzo, MD  more...
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The prognosis for full functional recovery in cases of patellofemoral syndrome is very good. In general, this syndrome is successfully treated with conservative measures. Because the prognosis is so good, refractory cases should be closely reviewed with regard to compliance and understanding of treatment recommendations.

A randomized, controlled trial suggested that gender and the duration of symptom complaints are predictive of which patients with PFS will respond to exercise therapy. The study, which included 131 patients who were randomized to receive exercise therapy or usual care, found that among patients in the exercise group, females and patients who had complained of symptoms for more than 6 months were more likely to report having achieved functional improvement beyond that of the usual-care patients at 3-month follow-up. [24]

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