Which medications in the drug class Progestins are used in the treatment of Hypoventilation Syndromes?

Updated: Jul 22, 2021
  • Author: Jazeela Fayyaz, DO; Chief Editor: Guy W Soo Hoo, MD, MPH  more...
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Answer

Progestins

These agents stimulate the central respiratory drive and may be beneficial in patients with hypoventilation.

Medroxyprogesterone acetate (Provera, Depo-Provera)

Medroxyprogesterone acetate increases the central respiratory drive and stimulates ventilation. It may increase upper airway muscular tone. For the treatment of hypoventilation, higher doses than usual of medroxyprogesterone acetate are required to induce significant reductions in hypercapnia.


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