What is the role of ventilatory assistance in chronic hypoventilation syndromes?

Updated: Jul 22, 2021
  • Author: Jazeela Fayyaz, DO; Chief Editor: Guy W Soo Hoo, MD, MPH  more...
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Noninvasive ventilation using nocturnal bilevel PPV using a mask interface is widely accepted as the ventilatory mode of choice in patients with chronic respiratory failure related to COPD, neuromuscular disease, thoracic deformities, and idiopathic hypoventilation. Nocturnal bilevel PPV acts by reducing nocturnal hypoventilation and increasing carbon dioxide responsiveness. [15] Nocturnal bilevel PPV may obviate the need for tracheotomy and has improved many patient-oriented outcomes. Bilevel PPV is the preferred method of noninvasive ventilation. [16, 17]

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