What are the risk factors for hypoventilation in severe COPD (COPD)?

Updated: Jul 22, 2021
  • Author: Jazeela Fayyaz, DO; Chief Editor: Guy W Soo Hoo, MD, MPH  more...
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Hypoventilation is not uncommon in patients with severe COPD. Alveolar hypoventilation in COPD usually does not occur unless the forced expiratory volume in 1 second (FEV1) is less than 1L or 30% of the predicted value. However, many patients with severe airflow obstruction do not develop hypoventilation. Therefore, other factors, such as abnormal control of ventilation, genetic predisposition, and respiratory muscle weakness, are likely to contribute.

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