How does noninvasive ventilation (NIV) affect the risk for nosocomial pneumonia in chronic obstructive pulmonary disease (COPD) patients?

Updated: Jun 18, 2020
  • Author: Guy W Soo Hoo, MD, MPH; Chief Editor: Zab Mosenifar, MD, FACP, FCCP  more...
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Answer

Another benefit with noninvasive ventilation may be a reduction in nosocomial infections associated with its application. This was a finding suggested by earlier investigations, because averting endotracheal intubation also avoids a major risk factor for ventilator-associated pneumonia (ie, the endotracheal tube). Experience in a case-control study suggests a reduction in nosocomial pneumonia from 22% to 8%, with fewer days in the ICU and lower mortality (26% down to >4%) in those treated with noninvasive ventilation as opposed to those who received endotracheal intubation. [18, 19]


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