Which conditions are associated with hypoxia despite mechanical ventilation?

Updated: Apr 11, 2019
  • Author: Christopher D Jackson, MD; Chief Editor: Zab Mosenifar, MD, FACP, FCCP  more...
  • Print
Answer

Answer

Inadequate oxygenation despite the administration of 100% oxygen should lead to a search for complications of endotracheal intubation (eg, right mainstem intubation) or positive-pressure breathing (pneumothorax). If such complications are not present, PEEP is needed to treat the intrapulmonary shunt pathology. Because only a few disease processes can create an intrapulmonary shunt, a clinically significant estimated shunt should narrow the potential source of hypoxemia to the following conditions:

  • Alveolar collapse - Major atelectasis

  • Alveolar filling with something other than gas - Lobar pneumonia

  • Water and protein - ARDS

  • Water - Congestive heart failure

  • Blood - Hemorrhage


Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!