What are indications for fractional exhaled nitric oxide (FENO) measurement?

Updated: May 14, 2020
  • Author: Kevin McCarthy, RPFT; Chief Editor: Nader Kamangar, MD, FACP, FCCP, FCCM  more...
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Common reasons for obtaining a FENO test include the following [21, 22] :

  • Assessment of cough, wheezing, and dyspnea

  • Identifying eosinophilic asthma phenotype

  • Assessing the potential response to anti-inflammatory agents, notably inhaled corticosteroids (ICS)

  • Establish a baseline FENO during a period of clinical stability for subsequent monitoring of chronic persistent asthma

  • To guide changes in anti-inflammatory medications in a step-wise manner

  • To assist in the evaluation of adherence to anti-inflammatory medications

  • To assess whether airway inflammation is contributing to poor asthma control, particularly in the presence of other contributors (eg, rhinosinusitis, anxiety, gastroesophageal reflux, obesity, continued allergen exposure)

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