How are patient's diffusing capacity of lung for carbon monoxide (DLCO) values adjusted in pulmonary function testing?

Updated: May 14, 2020
  • Author: Kevin McCarthy, RPFT; Chief Editor: Nader Kamangar, MD, FACP, FCCP, FCCM  more...
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Answer

Answer

Adjusting the patient’s measured DLCO value for the measured hemoglobin (not currently recommended but still commonly used) is as follows:

  • Adolescent males and men: Hb adjusted DLCO (DLCOc) = measured DLCO ([10.22 + Hb g/dL]/[1.7 Hb])
  • Children younger than 15 years and women: Hb adjusted DLCO (DLCOc) = measured DLCO ([9.38 + Hb g/dL]/[1.7 Hb])

Adjusting the predicted DLCO (and lower limit of normal) for the patient’s measured hemoglobin (currently recommended) is as follows:

  • Adolescent males and men: DLCO (predicted for Hb) = DLCO (predicted) x (1.7 Hb/(10.22 + Hb))
  • Children younger than 15 years and women: DLCO (predicted for Hb) = DLCO (predicted) x (1.7 Hb/(9.38 + Hb))

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