Which medications in the drug class Cardiac Glycosides are used in the treatment of Pulmonary Arterial Hypertension?

Updated: Apr 25, 2018
  • Author: Kristin E Schwab, MD; Chief Editor: Zab Mosenifar, MD, FACP, FCCP  more...
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Answer

Cardiac Glycosides

Cardiac glycosides are used for prevention and treatment of supraventricular arrhythmias associated with nonidiopathic pulmonary hypertension and for patients who have concomitant left-sided heart failure. Digoxin is not useful in the treatment of right-sided ventricular failure.

Digoxin (Lanoxin)

Digoxin is a cardiac glycoside with direct inotropic effects and indirect effects on the cardiovascular system. It acts directly on cardiac muscle, increasing myocardial systolic contractions. Its indirect actions result in increased carotid sinus nerve activity and enhanced sympathetic withdrawal for any given increase in mean arterial pressure.


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