Which medications in the drug class Anticoagulants are used in the treatment of Pulmonary Arterial Hypertension?

Updated: Apr 25, 2018
  • Author: Kristin E Schwab, MD; Chief Editor: Zab Mosenifar, MD, FACP, FCCP  more...
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Answer

Anticoagulants

Long-term anticoagulation with warfarin should be considered in selected patients with PAH. These include patients with chronic pulmonary embolism, pulmonary veno-occlusive disease, and atrial fibrillation induced by left- or right-sided heart failure who are at high risk for developing venous thromboembolism (eg, those with cor pulmonale or immobility secondary to severe dyspnea).

Warfarin (Coumadin, Jantoven)

Warfarin interferes with hepatic synthesis of vitamin K–dependent coagulation factors. It is used for prophylaxis and treatment of venous thrombosis, pulmonary embolism, and thromboembolic disorders.


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