When is calcium channel blocker therapy indicated to treat pulmonary arterial hypertension (PAH)?

Updated: Apr 25, 2018
  • Author: Kristin E Schwab, MD; Chief Editor: Zab Mosenifar, MD, FACP, FCCP  more...
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Answer

Advanced therapies should be considered after right-sided heart catheterization for PAH patients in functional class II, III, or IV. Patients with IPAH, heritable PAH, or anorexigen-induced PAH should undergo a vasoreactivity test as these patients may be candidates for calcium channel blockers (per below). Of note, even in this subset of patients, only a small minority of patients are vasoreactive and thus candidates for calcium channel blocker therapy.


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