What are the complications of restrictive lung disease?

Updated: Sep 16, 2020
  • Author: Jonathan Robert Caronia, DO; Chief Editor: John J Oppenheimer, MD  more...
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Acute exacerbation in patients with IPF is a recognized complication that occurs unpredictably and presents as worsening dyspnea. [28] Chest radiography demonstrates bilateral mixed alveolar-interstitial infiltrates, and CT scanning reveals ground-glass opacities and consolidation. Treatment includes high-dose systemic corticosteroids, although these are likely not effective, and the worsening disease portends an extremely poor prognosis. Series of patients with acute exacerbation of IPF reported in-hospital mortality rates between 78% and 96%. [29, 30, 31, 32]

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