Which medications in the drug class Oral Prostacyclin Analogues are used in the treatment of Idiopathic Pulmonary Arterial Hypertension?

Updated: Jul 08, 2020
  • Author: Ronald J Oudiz, MD, FACP, FACC, FCCP; Chief Editor: Zab Mosenifar, MD, FACP, FCCP  more...
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Answer

Oral Prostacyclin Analogues

Oral prostacyclin (PGI2) synthetic analogues are an alternative to parenteral administration.

Treprostinil tablet (Orenitram)

Treprostinil extended-release tablets are the first oral prostacyclin analogue approved by the FDA for PAH. It acts by causing vasodilation toboth pulmonary and systemic arterial vascular beds. It also decreases ventricular afterload and inhibits platelet aggregation.


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