Which hereditary factors are increase the risk of pulmonary embolism (PE)?

Updated: Sep 18, 2020
  • Author: Daniel R Ouellette, MD, FCCP; Chief Editor: Zab Mosenifar, MD, FACP, FCCP  more...
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Hereditary factors associated with the development of pulmonary embolism include the following:

  • Antithrombin III deficiency

  • Protein C deficiency

  • Protein S deficiency

  • Factor V Leiden (most common genetic risk factor for thrombophilia)

  • Plasminogen abnormality

  • Plasminogen activator abnormality

  • Fibrinogen abnormality

  • Resistance to activated protein C

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