What are the treatment options for varicella-zoster virus (VZV) pneumonia?

Updated: Mar 24, 2021
  • Author: Zab Mosenifar, MD, FACP, FCCP; Chief Editor: John J Oppenheimer, MD  more...
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Answer

Treatment of varicella pneumonia includes respiratory isolation until skin lesions heal, supportive care, administration of antiviral agents, and active and passive immunization. For treatment of documented varicella pneumonia in patients who are immunocompromised, acyclovir (10 mg/kg IV q8h for 7 d) has been shown to be effective.

For pregnant women in the third trimester, acyclovir at 10 mg/kg IV every eight hours for five days should be given, and consideration should be given for varicella-zoster immune globulin (VZIG) therapy.


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