Which histologic findings are characteristic of Hantavirus pulmonary syndrome (HPS) and pneumonia?

Updated: Mar 24, 2021
  • Author: Zab Mosenifar, MD, FACP, FCCP; Chief Editor: John J Oppenheimer, MD  more...
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Hantavirus pneumonia histopathology reveals interstitial infiltrates of T lymphocytes and alveolar pulmonary edema without marked necrosis or polymorphonuclear leukocyte involvement. This finding is consistent with the pathogenesis being mainly caused by vascular permeability increase, via an immunopathologic mechanism. [76]

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