Which findings on chest radiography are characteristic of Hantavirus pulmonary syndrome (HPS)?

Updated: Mar 24, 2021
  • Author: Zab Mosenifar, MD, FACP, FCCP; Chief Editor: John J Oppenheimer, MD  more...
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Hantavirus infection may show a normal chest radiograph during early disease. This is followed by signs of interstitial edema, Kerley B lines, peribronchial cuffing, and indistinct hila. Progression to the pulmonary edema phase over the subsequent 48 hours is indicated by centrally located dense alveolar infiltrates, unlike the more peripheral infiltrates of ARDS from other causes. With further progression, pleural effusions also may develop.

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