What are the guidelines on pneumococcal vaccinations for the prevention of bacterial pneumonia?

Updated: Sep 30, 2020
  • Author: Justina Gamache, MD; Chief Editor: Guy W Soo Hoo, MD, MPH  more...
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Vaccination and other prevention guidelines are briefly discussed below.

Pneumococcal vaccine recommendations

In 2015, the Advisory Committee on Immunization Practices provided recommendations on the pneumococcal polysaccharide vaccine (PPSV23) and the pneumococcal conjugate vaccine (PCV13), summarized as follows [72, 73] :

  • For immunocompetent adults aged  65 years and older who have not previously received pneumococcal vaccine, the Advisory Committee on Immunization Practices (ACIP) makes the following recommendation for intervals between pneumococcal conjugate vaccine (PCV13) followed by pneumococcal polysaccharide vaccine (PPSV23): A dose of PPSV23 should be given 1 year or more following a dose of PCV13. The 2 vaccines should not be co-administered. If a dose of PPSV23 is inadvertently given earlier than the recommended interval, the dose need not be repeated.
  • The ACIP currently recommends that a dose of PCV13 be followed by a dose of PPSV23 in persons aged 2 years or older who are at high risk for pneumococcal disease because of underlying medical conditions.
  • Children with an immunocompromising condition or functional or anatomic asplenia should receive a second dose of PPSV23 5 years after the first PPSV23 dose.

See Vaccinations - Adult and Vaccinations - Infants and Children for more information.

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