Which empiric antibiotics are indicated in patients with bacterial pneumonia and a greater risk of anaerobic infection?

Updated: Sep 30, 2020
  • Author: Justina Gamache, MD; Chief Editor: Guy W Soo Hoo, MD, MPH  more...
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Answer

Patients with severe periodontal disease, putrid sputum, or a history of alcoholism with suspected aspiration pneumonia may be at greater risk of anaerobic infection. One of the following antibiotic regimens is suggested for such patients [3, 17] :

  • Piperacillin-tazobactam

  • Imipenem

  • Clindamycin or metronidazole plus a respiratory fluoroquinolone plus ceftriaxone


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