What is the role of antigen-antibody testing in the workup of Legionella pneumonia?

Updated: Sep 30, 2020
  • Author: Justina Gamache, MD; Chief Editor: Guy W Soo Hoo, MD, MPH  more...
  • Print

Urinary antigen testing for Legionella serogroup 1 organisms is accurate. However, as many as 30% of infections are not caused by serogroup 1 organisms. A Legionella serum antibody titer of 1:128 or more is suggestive of the diagnosis. Pneumococcal antigen tests for serum, urine, and saliva samples have been developed. Antigen-antibody testing has little clinical effect in an emergency department setting, although it may help in recalcitrant or unclear cases.

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!