What is the role of pulmonary function testing in the workup of hypersensitivity pneumonitis (HP)?

Updated: Oct 08, 2020
  • Author: Caleb Hsieh, MD, MS; Chief Editor: John J Oppenheimer, MD  more...
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Answer

A restrictive ventilatory pattern, with reduced forced vital capacity, total lung capacity, and preserved airflow, is observed in acute or subacute disease. A restrictive (severe) or a mixed obstructive and restrictive pattern is common in chronic hypersensitivity pneumonitis (HP). Diffusing capacity of lungs for carbon monoxide is reduced in all forms of hypersensitivity pneumonitis. Many patients have hypoxemia at rest, and most patients desaturate with exercise.


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