Which autoimmune disorders are associated with bronchiectasis?

Updated: Jul 23, 2019
  • Author: Ethan E Emmons, MD; Chief Editor: Zab Mosenifar, MD, FACP, FCCP  more...
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Answer

Rheumatoid arthritis is associated with bronchiectasis in a reported 3.2-35% of patients [52, 53, 54] and, in one series, was associated with an unfavorable prognosis. [55] The pathology of bronchiectasis may be increased susceptibility to infections in these patients. Pulmonary disease may occur prior to the onset of the rheumatic process.

Bronchiectasis has been noted in patients with Sjögren syndrome and may be secondary to increased viscosity of mucus with poor airway clearance. [56]

Ankylosing spondylitis is associated with bronchiectasis, but in small numbers. [57]

Systematic lupus erythematosus may present with a variety of pulmonary pathology, including bronchiectasis, which was reported in 21% of patients in one series. [58]


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