When is ipratropium indicated in the treatment of acute asthma?

Updated: Jan 07, 2019
  • Author: Michael J Morris, MD, FACP, FCCP; Chief Editor: Zab Mosenifar, MD, FACP, FCCP  more...
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Answer

Ipratropium 0.5 mg has had variable benefit in controlled trials, demonstrating most consistent efficacy in children and smokers with comorbid COPD. The current NAEPP guidelines (2007) recommend its use in severe exacerbations only. [1] Ipratropium should be given in combination with albuterol every 20 minutes for 3 doses, then as needed. The addition of ipratropium has not been shown to provide further benefit once the patient is hospitalized.


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