What are the IDSA and ATS guidelines for treatment of aspiration pneumonia caused by MRSA infection?

Updated: Aug 15, 2018
  • Author: Justina Gamache, MD; Chief Editor: Guy W Soo Hoo, MD, MPH  more...
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The 2011 Infectious Diseases Society of America (IDSA) guidelines for the management of MRSA infections include the following recommendations for the treatment of pneumonia [20] :

  • Empirical therapy for MRSA pending laboratory results for patients with community-acquired pneumonia (CAP) and any of the following: (1) admission to the ICU; (2) necrotizing or cavitary infiltrates; or (3) empyema
  • In patients with MRSA pneumonia complicated by empyema, antimicrobial therapy should be used in conjunction with drainage procedures

The 2016 IDSA and American Thoracic Society (ATS) guidelines for the management of MRSA pneumonia recommends the following for treatment strategies [21] :

  • Intravenous vancomycin or linezolid for 7 days
  • De-escalation of antibiotic regimen as indicated based on culture data and clinical course

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