What is the role of liver transplantation in the treatment of alpha1-antitrypsin deficiency (AATD)?

Updated: Sep 11, 2020
  • Author: Dora E Izaguirre Anariba, MD, MPH; Chief Editor: John J Oppenheimer, MD  more...
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Answer

Liver transplantation is the definitive treatment for advanced liver disease. [3] Despite the normalization of AAT levels after liver transplantation, the FEV1 continues to decline unexpectedly after liver transplantation in some ZZ or SZ phenotype patients. [22]


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