What are the presenting features of Binswanger disease in patients with vascular dementia?

Updated: Mar 26, 2018
  • Author: Kannayiram Alagiakrishnan, MD, MBBS, MPH, MHA; Chief Editor: Glen L Xiong, MD  more...
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Answer

The average age of onset is between the fourth and seventh decades of life, and 80% of patients have a history of hypertension. Patients also show progressive motor, cognitive, mood, and behavioral changes over a period of 5-10 years. Mood and behavioral changes are observed early and, in some patients, may be the presenting feature. Patients may be apathetic or abulic.

Intellectual deficits are also observed early in the disease, and patients are frequently described as disoriented, having memory deficits, inattentive, and vague.

Patients with Binswanger dementia often have early-onset urinary incontinence and gait disturbances.


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