What is the role of leukoaraiosis in vascular dementia?

Updated: Mar 26, 2018
  • Author: Kannayiram Alagiakrishnan, MD, MBBS, MPH, MHA; Chief Editor: Glen L Xiong, MD  more...
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Answer

Leukoaraiosis (or white matter hyperintensities) greater than 25% is considered to be pathological. Subcortical vascular dementia is a diffuse small vessel disease with minimal or absent infarction with homogenous pathological and clinical features. [3, 4] White matter ischemic changes affect executive dysfunction and cause slower processing speed, rather than memory and language impairment. [5]


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