How is persistent depressive disorder (dysthymia) treated?

Updated: Oct 01, 2019
  • Author: Jerry L Halverson, MD; Chief Editor: David Bienenfeld, MD  more...
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Psychotherapy and medication management are effective treatment modalities for dysthymia, and combination treatment is common. Minimal data are available; however, a randomized trial that compared interpersonal psychotherapy, brief supportive psychotherapy, sertraline treatment alone, and sertraline treatment plus interpersonal psychotherapy found the greatest effect when sertraline and interpersonal therapy were combined.

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