Is cognitive remediation therapy effective for schizophrenia?

Updated: Mar 16, 2018
  • Author: Frances R Frankenburg, MD; Chief Editor: Glen L Xiong, MD  more...
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Answer

In a study by Grant et al, low-functioning patients with prominent negative symptoms were assigned to either recovery-oriented cognitive-behavioral therapy plus standard treatment or standard treatment; after 18 months, the authors found that both negative and positive symptoms had decreased in the group receiving the add-on cognitive therapy. [118] The study was not blinded, and the treatment was delivered by enthusiastic doctoral level therapists; thus, the findings may not be widely generalizable.

A study by Puig and colleagues also found cognitive remediation therapy to be effective. In the study, 50 patients between the ages of 12 and 18 years with early onset schizophrenia were randomized to either cognitive remediation therapy plus usual treatment or usual treatment alone. Patients in the cognitive remediation group showed significantly greater improvements than patients in the usual treatment group in verbal memory, working memory, executive function, and cognitive composite scores, at the end of treatment and at 3-month follow-up. The cognitive remediation group also had greater improvements in daily living skills, global adaptive functioning, and self-perceived family burden. [119]


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